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Western blot(SDS PAGE) analysis of extracts from HeLa cell lysate.Using Cytokeratin 18 Rabbit mAb [XxIB]at dilution of 1:1000 incubated at 4℃ over night.
Protein names :type I cytoskeletal 18; Cell proliferation-inducing gene 46 protein; Cytokeratin-18; Keratin-18; KRT18; CYK18; PIG46; KRT 18; CK18; Keratin 18;
UniProtID :P05783
MASS(da) :48,058
MW(kDa) :43,48kDa
Form :Liquid
Purification :Affinity-chromatography
Host :Rabbit
Isotype : IgG
sensitivity :Endogenous
Reactivity :Human,Mouse,Rat
Specificity :Antibody is produced by immunizing animals with A synthesized peptide derived from human Cytokeratin 18
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :HeLa cell lysate.
Function : Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection..
Tissue specificity :Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma..
Subcellular locationi :Cytoplasm, perinuclear region. Nucleus, nucleolus.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.