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Western blot(SDS PAGE) analysis of extracts from Jurkat cell lysate.Using IRF6 Rabbit mAb [Gd4X]at dilution of 1:1000 incubated at 4℃ over night.
Protein names :Interferon regulatory factor 6; IRF 6; LPS;OFC 6; PIT; PPS; PPS1; VWS; VWS1;
UniProtID :O14896
MASS(da) :53,130
MW(kDa) :53kDa
Form :Liquid
Purification :Affinity-chromatography
Host :Rabbit
Isotype : IgG
sensitivity :Endogenous
Reactivity :Human,Mouse,Rat
Specificity :Antibody is produced by immunizing animals with A synthesized peptide derived from human IRF6
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :Jurkat cell lysate.
Function : Probable DNA-binding transcriptional activator. Key determinant of the keratinocyte proliferation-differentiation switch involved in appropriate epidermal development (By similarity). Plays a role in regulating mammary epithelial cell proliferation (By similarity). May regulate WDR65 transcription (By similarity)..
Tissue specificity :Expressed in normal mammary epithelial cells. Expression is reduced or absent in breast carcinomas..
Subcellular locationi :Nucleus. Cytoplasm.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.