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Western blot(SDS PAGE) analysis of extracts from 293T cell lysate.Using MRC1 Rabbit mAb [dg1n]at dilution of 1:1000 incubated at 4℃ over night.
Protein names :Macrophage mannose receptor 1; MMR; CD206 antigen; MRC1; Mannose receptor C type 1;
UniProtID :P22897
MASS(da) :166,012
MW(kDa) :166kDa
Form :Liquid
Purification :Affinity-chromatography
Host :Rabbit
Isotype : IgG
sensitivity :Endogenous
Reactivity :Human
Specificity :Antibody is produced by immunizing animals with A synthesized peptide derived from human MRC1
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :293T cell lysate.
Function : Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains., (Microbial infection) Acts as phagocytic receptor for bacteria, fungi and other pathogens., (Microbial infection) Acts as a receptor for Dengue virus envelope protein E.., (Microbial infection) Interacts with Hepatitis B virus envelope protein..
Subcellular locationi :Endosome membrane,Single-pass type I membrane protein. Cell membrane,Single-pass type I membrane protein.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.