67kDa Laminin Receptor Rabbit mAb [t8Cw]Cat NO.: A28599

Protein names ：RPSA; 37LRP; 67LR; LAMR1; LAMBR; LamR; LRP/LR; RSSA;

UniProtID ：P08865

MASS(da) ：32,854

MW(kDa) ：42kDa

Form ：Liquid

Purification ：Affinity-chromatography

Host ：Rabbit

Isotype ： IgG

sensitivity ：Endogenous

Reactivity ：Human,Mouse,Rat

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• 免疫组化(IHC)1:100
• 免疫荧光(ICC/IF)1:100
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with A synthesized peptide derived from human 67kDa Laminin Receptor

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：(1) HeLa cell lysate; (2) NIH/3T3 cell lysate; (3) PC-12 cell lysate.

Function ： Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA.., (Microbial infection) Acts as a receptor for the Adeno-associated viruses 2,3,8 and 9.., (Microbial infection) Acts as a receptor for the Dengue virus.., (Microbial infection) Acts as a receptor for the Sindbis virus.., (Microbial infection) Acts as a receptor for the Venezuelan equine encephalitis virus.., (Microbial infection) Acts as a receptor for the pathogenic prion protein.., (Microbial infection) Acts as a receptor for bacteria..

Subcellular locationi ：Cell membrane. Cytoplasm. Nucleus.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.