PD-L2 Rabbit mAb [63J5]Cat NO.: A54859

Protein names ：PDCD1LG2,B7DC,CD273,PDCD1L2,PDL2,PD1L2_HUMAN,Programmed cell death 1 ligand 2

UniProtID ：Q9BQ51

MASS(da) ：30,957

MW(kDa) ：45-60 kDa

Form ：Liquid

Purification ：Protein A purification

Host ：Rabbit

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Human

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide at the sequence of Human PD-L2

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：Jurkat cells

Function ： Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity)..

Tissue specificity ：Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus..

Subcellular locationi ：[Isoform 3]: Secreted.,[Isoform 2]: Endomembrane system,Single-pass type I membrane protein.,[Isoform 1]: Cell membrane,Single-pass type I membrane protein.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.