Neutrophil Elastase Rabbit mAb [Y93G]Cat NO.: A84255

Protein names ：ELA2; ELANE; Elastase 2; Medullasin; Neutrophil elastase; PMN E; SCN1;

UniProtID ：P08246

MASS(da) ：28,518

MW(kDa) ：29kDa

Form ：Liquid

Purification ：Affinity-chromatography

Host ：Rabbit

Isotype ： IgG

sensitivity ：Endogenous

Reactivity ：Human

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• 免疫组化(IHC)1:100
• 免疫荧光(ICC/IF)1:100
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with A synthesized peptide derived from human Neutrophil Elastase

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：HL60 cell lysate.

Function ： Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis (PubMed:15140022). Capable of killing E.coli but not S.aureus in vitro,digests outer membrane protein A (ompA) in E.coli and K.pneumoniae (PubMed:10947984)..

Tissue specificity ：Bone marrow cells. Neutrophil (PubMed:10947984)..

Subcellular locationi ：Cytoplasmic vesicle, phagosome.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.