PDE4D Rabbit mAb [MeRR]Cat NO.: A55270

Protein names ：cAMP-specific 3',5'-cyclic phosphodiesterase 4D; DPDE3; PDE43; PDE4D; DPDE3;

UniProtID ：Q08499

MASS(da) ：91,115

MW(kDa) ：91kDa

Form ：Liquid

Purification ：Affinity-chromatography

Host ：Rabbit

Isotype ： IgG

sensitivity ：Endogenous

Reactivity ：Human

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with A synthesized peptide derived from human PDE4D

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：human fetal heart lysate.

Function ： Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes..

Tissue specificity ：Expressed in colonic epithelial cells (at protein level). Widespread,most abundant in skeletal muscle..,[Isoform 6]: Detected in brain..,[Isoform 8]: Detected in brain, placenta, lung and kidney..,[Isoform 7]: Detected in heart and skeletal muscle..

Subcellular locationi ：Apical cell membrane. Cytoplasm. Membrane. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.