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Western blot(SDS PAGE) analysis of extracts from Jurkat cell lysate.Using Prolactin Receptor Rabbit mAb [ow1D]at dilution of 1:1000 incubated at 4℃ over night.
Protein names :CPRLP; HPRL; hPRL receptor; Lactogen receptor; MFAB; OPR; Pr-1; Pr-3; PRLR; Prolactin receptor a;
UniProtID :P16471
MASS(da) :69,506
MW(kDa) :95kDa
Form :Liquid
Purification :Affinity-chromatography
Host :Rabbit
Isotype : IgG
sensitivity :Endogenous
Reactivity :Human,Mouse,Rat
Specificity :Antibody is produced by immunizing animals with A synthesized peptide derived from human Prolactin Receptor
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :Jurkat cell lysate.
Function : This is a receptor for the anterior pituitary hormone prolactin (PRL). Acts as a prosurvival factor for spermatozoa by inhibiting sperm capacitation through suppression of SRC kinase activation and stimulation of AKT. Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling..
Tissue specificity :Expressed in breast, placenta, kidney, liver and pancreas..
Subcellular locationi :Membrane,Single-pass type I membrane protein.,[Isoform 7]: Secreted.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.