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Western blot(SDS PAGE) analysis of extracts from SH-SY5Y cell lysate.Using PSD93 Rabbit mAb [r9D8]at dilution of 1:1000 incubated at 4℃ over night.
Protein names :Chapsyn110; dlg2; Dlgh2; Gm1197; PSD93;
UniProtID :Q15700
MASS(da) :97,552
MW(kDa) :110kDa
Form :Liquid
Purification :Affinity-chromatography
Host :Rabbit
Isotype : IgG
sensitivity :Endogenous
Reactivity :Human,Mouse,Rat
Specificity :Antibody is produced by immunizing animals with A synthesized peptide derived from human PSD93
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :SH-SY5Y cell lysate.
Function : Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses (By similarity)..
Subcellular locationi :Cell membrane,Lipid-anchor. Cell junction, synapse, postsynaptic density. Cell junction, synapse. Membrane. Cell projection, axon. Perikaryon.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.