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Western blot(SDS PAGE) analysis of extracts from Human cerebellum lysate.Using GABA A Receptor beta 1 Rabbit mAb [2Jo5]at dilution of 1:1000 incubated at 4℃ over night.
Protein names :GABA-A receptor, beta-1 polypeptide; Gabrb-1; GABRB1; GARB1;
UniProtID :P18505
MASS(da) :54,235
MW(kDa) :48kDa
Form :Liquid
Purification :Affinity-chromatography
Host :Rabbit
Isotype : IgG
sensitivity :Endogenous
Reactivity :Human,Mouse,Rat
Specificity :Antibody is produced by immunizing animals with A synthesized peptide derived from human GABA A Receptor beta 1
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :Human cerebellum lysate.
Function : Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital,these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel..
Subcellular locationi :Cell junction, synapse, postsynaptic cell membrane,Multi-pass membrane protein. Cell membrane,Multi-pass membrane protein.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.