TGF alpha Rabbit mAb [fTI4]Cat NO.: A21965

Protein names ：ETGF; TFGA; TGF A; TGF-alpha; Tgfa; Wa1; Waved 1;

UniProtID ：P01135

MASS(da) ：17,006

MW(kDa) ：15kDa

Form ：Liquid

Purification ：Affinity-chromatography

Host ：Rabbit

Isotype ： IgG

sensitivity ：Endogenous

Reactivity ：Human

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• 免疫组化(IHC)1:100
• 免疫荧光(ICC/IF)1:100
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with A synthesized peptide derived from human TGF alpha

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：(1) HepG2 cell lysate; (2) Human fetal liver lysate.

Function ： TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar.

Tissue specificity ：Isoform 1, isoform 3 and isoform 4 are expressed in keratinocytes and tumor-derived cell lines..

Subcellular locationi ：[Transforming growth factor alpha]: Secreted, extracellular space.,[Protransforming growth factor alpha]: Cell membrane,Single-pass type I membrane protein.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.