CD89 Rabbit mAb [xz5g]Cat NO.: A33793

Protein names ：CD89; Fc alpha receptor; FCAR; IgA Fc receptor;

UniProtID ：P24071

MASS(da) ：32,265

MW(kDa) ：70kDa

Form ：Liquid

Purification ：Affinity-chromatography

Host ：Rabbit

Isotype ： IgG

sensitivity ：Endogenous

Reactivity ：Human

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• 免疫组化(IHC)1:100
• 免疫荧光(ICC/IF)1:100
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with A synthesized peptide derived from human CD89

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：HL-60 cell lysate.

Function ： Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production..

Tissue specificity ：Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells. Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are expressed in alveolar macrophages,however only one isoform is expressed at alveolar macrophages surfaces..

Subcellular locationi ：[Isoform A.1]: Cell membrane,Single-pass type I membrane protein.,[Isoform A.2]: Cell membrane,Single-pass type I membrane protein.,[Isoform A.3]: Cell membrane,Single-pass type I membrane protein.,[Isoform B]: Secreted.,[Isoform B-delta-S2]: Secreted.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.