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Western blot(SDS PAGE) analysis of extracts from U87-MG cell lysate.Using Cathepsin S Rabbit mAb [b5D1]at dilution of 1:1000 incubated at 4℃ over night.
Protein names :CTSS; Cathepsin S; Cat-s; CATS;
UniProtID :P25774
MASS(da) :37,496
MW(kDa) :25kDa
Form :Liquid
Purification :Affinity-chromatography
Host :Rabbit
Isotype : IgG
sensitivity :Endogenous
Reactivity :Human
Specificity :Antibody is produced by immunizing animals with A synthesized peptide derived from human Cathepsin S
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :U87-MG cell lysate.
Function : Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules and MHC class II antigen presentation (PubMed:30612035). The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L..
Subcellular locationi :Lysosome. Secreted. Cytoplasmic vesicle, phagosome.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.