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USP22 Rabbit mAb [P5rl]Cat NO.: A45705

Western blot(SDS PAGE) analysis of extracts from (1) HeLa cell lysate; (2) Mouse spleen lysate.Using USP22 Rabbit mAb [P5rl]at dilution of 1:1000 incubated at 4℃ over night.

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Product information

Protein names :Ubiquitin carboxyl terminal hydrolase 22; Usp22; USP3L;

UniProtID :Q9UPT9

MASS(da) :59,961

MW(kDa) :60kDa

Form :Liquid

Purification :Affinity-chromatography

Host :Rabbit

Isotype : IgG

sensitivity :Endogenous

Reactivity :Human,Mouse,Rat

  • ApplicationDilution
  • 免疫印迹(WB)1:1000-2000
  • 免疫荧光(ICC/IF)1:100
  • The optimal dilutions should be determined by the end user

Specificity :Antibody is produced by immunizing animals with A synthesized peptide derived from human USP22

Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected :(1) HeLa cell lysate; (2) Mouse spleen lysate.

Function : Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression..

Tissue specificity :Moderately expressed in various tissues including heart and skeletal muscle, and weakly expressed in lung and liver..

Subcellular locationi :Nucleus.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.