TIMM50 Rabbit mAb [83hk]Cat NO.: A18981

Protein names ：TIM50; TIM50L; TIMM50;

UniProtID ：Q3ZCQ8

MASS(da) ：39,646

MW(kDa) ：36kDa

Form ：Liquid

Purification ：Affinity-chromatography

Host ：Rabbit

Isotype ： IgG

sensitivity ：Endogenous

Reactivity ：Human Mouse

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• 免疫组化(IHC)1:100
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with A synthesized peptide derived from human TIMM50

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：293T cell lysate.

Function ： Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro,however such activity may not be relevant in vivo.., [Isoform 2]: May participate in the release of snRNPs and SMN from the Cajal body..

Tissue specificity ：Widely expressed. Expressed at higher level in brain, kidney and liver (at protein level)..

Subcellular locationi ：Mitochondrion inner membrane,Single-pass membrane protein.,[Isoform 2]: Nucleus speckle.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.