SRD5A2 Rabbit mAb [0WD0]Cat NO.: A57745

Protein names ：SRD5A2; 5 alpha-SR2; S5AR 2; Type II 5-alpha reductase; SR type 2; Steroid 5-alpha-reductase 2;

UniProtID ：P31213

MASS(da) ：28,393

MW(kDa) ：28kDa

Form ：Liquid

Purification ：Affinity-chromatography

Host ：Rabbit

Isotype ： IgG

sensitivity ：Endogenous

Reactivity ：Human Rat

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with A synthesized peptide derived from human SRD5A2

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：PC3 cell lysate.

Function ： Converts testosterone (T) into 5-alpha-dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology..

Tissue specificity ：Expressed in high levels in the prostate and many other androgen-sensitive tissues.

Subcellular locationi ：Microsome membrane,Multi-pass membrane protein. Endoplasmic reticulum membrane,Multi-pass membrane protein.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.