P2Y12 Rabbit mAb [A2B0]Cat NO.: A68706

Protein names ：ADP glucose receptor; ADPGR; BDPLT8; HORK3; P2RY12; P2Y purinoceptor 12; P2Y12; P2Y12 platelet ADP receptor; Platelet ADP receptor; Purinergic receptor P2RY12; Purinergic receptor P2Y12; SP1999;

UniProtID ：Q9H244

MASS(da) ：39,439

MW(kDa) ：50kDa

Form ：Liquid

Purification ：Affinity-chromatography

Host ：Rabbit

Isotype ： IgG

sensitivity ：Endogenous

Reactivity ：Human,Mouse,Rat

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with A synthesized peptide derived from human P2Y12

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：RAW 264.7 cell lysate.

Function ： Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Required for normal platelet aggregation and blood coagulation..

Tissue specificity ：Highly expressed in the platelets, lower levels in the brain. Lowest levels in the lung, appendix, pituitary and adrenal gland. Expressed in the spinal cord and in the fetal brain..

Subcellular locationi ：Cell membrane,Multi-pass membrane protein.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.