PCTAIRE1 Rabbit mAb [3Ilm]Cat NO.: A43254

Protein names ：Cdk16; PCTAIRE; PCTAIRE1; PCTGAIRE; PCTK1;

UniProtID ：Q00536

MASS(da) ：55,716

MW(kDa) ：62-68kDa

Form ：Liquid

Purification ：Affinity-chromatography

Host ：Rabbit

Isotype ： IgG

sensitivity ：Endogenous

Reactivity ：Human,Mouse,Rat

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with A synthesized peptide derived from human PCTAIRE1

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：BxPC-3 cell lysate.

Function ： Protein kinase that plays a role in vesicle-mediated transport processes and exocytosis. Regulates GH1 release by brain neurons. Phosphorylates NSF, and thereby regulates NSF oligomerization. Required for normal spermatogenesis. Regulates neuron differentiation and dendrite development (By similarity). Plays a role in the regulation of insulin secretion in response to changes in blood glucose levels. Can phosphorylate CCNY at 'Ser-336' (in vitro)..

Tissue specificity ：Detected in pancreas islets (at protein level). Detected in brain and pancreas..

Subcellular locationi ：Cytoplasm. Cytoplasmic vesicle, secretory vesicle. Cell membrane,Peripheral membrane protein,Cytoplasmic side. Cell junction, synapse, synaptosome.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.