ICAM1 / CD54 Rabbit mAb [vVs1]Cat NO.: A28171

Protein names ：BB2; CD54; Cell surface glycoprotein P3.58; Human rhinovirus receptor;ICAM1; intercellular adhesion molecule 1 (CD54); Intercellular adhesion molecule 1; Major group rhinovirus receptor;MALA2; MyD10; P3.58; Surface antigen of activated B cells;

UniProtID ：P13597(Mouse, 抗原), P13597(mouse)(human:P05362)

MASS(da) ：58,844

MW(kDa) ：80-110kDa

Form ：Liquid

Purification ：Affinity-chromatography

Host ：Rabbit

Isotype ： IgG

sensitivity ：Endogenous

Reactivity ：Mouse

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• 免疫组化(IHC)1:100
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with A synthesized peptide derived from human ICAM1 / CD54

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：various lysates

Function ： ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity)..

Tissue specificity ：Expressed at low level on a subpopulation of lymphocytes, macrophages, and endothelial cells, but is strongly induced on these cells, and on fibroblasts and epithelial cells.

Subcellular locationi ：Membrane,Single-pass type I membrane protein.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.