Huntingtin Rabbit mAb [Z46U]Cat NO.: A63409

Protein names ：HTT,HD,IT15,HD_HUMAN,Huntingtin [Cleaved into: Huntingtin, myristoylated N-terminal fragment]

UniProtID ：P42858

MASS(da) ：347,603

MW(kDa) ：348 kDa

Form ：Liquid

Purification ：Protein A purification

Host ：Rabbit

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Human,Mouse,Rat

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• 免疫组化(IHC)1:100
• 免疫荧光(ICC/IF) 1:100
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide at the sequence of human Huntingtin

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：SH-SY5Y cells

Function ： [Huntingtin]: May play a role in microtubule-mediated transport or vesicle function., [Huntingtin, myristoylated N-terminal fragment]: Promotes the formation of autophagic vesicles..

Tissue specificity ：Expressed in the brain cortex (at protein level). Widely expressed with the highest level of expression in the brain (nerve fibers, varicosities, and nerve endings). In the brain, the regions where it can be mainly found are the cerebellar cortex, the neocortex, the striatum, and the hippocampal formation..

Subcellular locationi ：[Huntingtin]: Cytoplasm. Nucleus. Early endosome.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.