p18 INK4c/CDKN2C Rabbit mAb [L3QM]Cat NO.: A14161

Protein names ：CDKN2C,CDKN6,CDN2C_HUMAN,Cyclin-dependent kinase 4 inhibitor C

UniProtID ：P42773

MASS(da) ：18,127

MW(kDa) ：18 kDa

Form ：Liquid

Purification ：Protein A purification

Host ：Rabbit

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Human,Mouse,Rat

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• 免疫组化(IHC)1:100
• 免疫荧光(ICC/IF) 1:100
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide at the sequence of human p18 INK4c/CDKN2C

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：HEL-293T cells

Function ： Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB.

Tissue specificity ：Highest levels found in skeletal muscle. Also found in pancreas and heart.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.