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CDKN2A/p14ARF Rabbit mAb [YYC6]Cat NO.: A10330

Western blot(SDS PAGE) analysis of extracts from HeLa cells .Using CDKN2A/p14ARFRabbit mAb [YYC6] at dilution of 1:1000 incubated at 4℃ over night.

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Product information

Protein names :CDKN2A,CDKN2,MTS1,CDN2A_HUMAN,Cyclin-dependent kinase inhibitor 2A

UniProtID :P42771 

MW(kDa) :14 kDa

Form :Liquid

Purification :Protein A purification

Host :Rabbit

Isotype :IgG

sensitivity :Endogenous

Reactivity :Human

  • ApplicationDilution
  • 免疫印迹(WB)1:1000-2000
  • 免疫荧光(ICC/IF) 1:100
  • The optimal dilutions should be determined by the end user

Specificity :Antibody is produced by immunizing animals with a synthetic peptide at the sequence of human CDKN2A/p14ARF

Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected :HeLa cells 

Function : Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein..

Tissue specificity :Widely expressed but not detected in brain or skeletal muscle. Isoform 3 is pancreas-specific..

Subcellular locationi :Cytoplasm. Nucleus.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.