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Western blot(SDS PAGE) analysis of extracts from T47-D cells.Using CD168Rabbit mAb [93JL] at dilution of 1:1000 incubated at 4℃ over night.
Protein names :HMMR,IHABP,RHAMM,HMMR_HUMAN,Hyaluronan mediated motility receptor
UniProtID :O75330
MASS(da) :84,100
MW(kDa) :85 kDa
Form :Liquid
Purification :Protein A purification
Host :Rabbit
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human
Specificity :Antibody is produced by immunizing animals with a synthetic peptide at the sequence of human CD168
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :T47-D cells
Function : Receptor for hyaluronic acid (HA) (By similarity). Involved in cell motility (By similarity). When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity. May act as a regulator of adipogenisis (By similarity)..
Tissue specificity :Expressed in testis (PubMed:22965910). Expressed in the breast (PubMed:8890751)..
Subcellular locationi :Cell surface. Cytoplasm. Cytoplasm, cytoskeleton, spindle.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.