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Western blot(SDS PAGE) analysis of extracts from Human fetal liver.Using P70 S6 Kinase beta/SRKRabbit mAb [9L7R] at dilution of 1:1000 incubated at 4℃ over night.
Protein names :RPS6KB2,STK14B,KS6B2_HUMAN,Ribosomal protein S6 kinase beta-2
UniProtID :Q9UBS0
MASS(da) :53,455
MW(kDa) :42 kDa
Form :Liquid
Purification :Protein A purification
Host :Rabbit
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human
Specificity :Antibody is produced by immunizing animals with a synthetic peptide at the sequence of human P70 S6 Kinase beta/SRK
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :Human fetal liver
Function : Phosphorylates specifically ribosomal protein S6 (PubMed:29750193). Seems to act downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression in an alternative pathway regulated by MEAK7 (PubMed:29750193)..
Subcellular locationi :Cytoplasm. Nucleus.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.