NSDHL Rabbit mAb [1M49]Cat NO.: A46398

Protein names ：NSDHL,H105E3,NSDHL_HUMAN,Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

UniProtID ：Q15738

MASS(da) ：41,900

MW(kDa) ：42 kDa

Form ：Liquid

Purification ：Protein A purification

Host ：Rabbit

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Human,Mouse,Rat

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide at the sequence of human NSDHL

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：HeLa cells

Function ： Catalyzes the NAD(P)(+)-dependent oxidative decarboxylation of the C4 methyl groups of 4-alpha-carboxysterols in post-squalene cholesterol biosynthesis (By similarity). Plays also a role in the regulation of the endocytic trafficking of EGFR (By similarity)..

Tissue specificity ：Brain, heart, liver, lung, kidney, skin and placenta.

Subcellular locationi ：Endoplasmic reticulum membrane,Single-pass membrane protein. Lipid droplet.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.