* 产品详情- */>
Western blot(SDS PAGE) analysis of extracts from HeLa cells.Using ATAD2Rabbit mAb [52VP] at dilution of 1:1000 incubated at 4℃ over night.
Protein names :ATAD2,L16,PRO2000,ATAD2_HUMAN,ATPase family AAA domain-containing protein 2
UniProtID :Q6PL18
MASS(da) :158,554
MW(kDa) :200 kDa
Form :Liquid
Purification :Protein A purification
Host :Rabbit
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human
Specificity :Antibody is produced by immunizing animals with a synthetic peptide at the sequence of human ATAD2
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :HeLa cells
Function : May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells..
Tissue specificity :Highly expressed in estrogen receptor positive breast tumors and in osteosarcoma tumors..
Subcellular locationi :Nucleus.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.