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ATAD2 Rabbit mAb [52VP]Cat NO.: A47307

Western blot(SDS PAGE) analysis of extracts from HeLa cells.Using ATAD2Rabbit mAb [52VP] at dilution of 1:1000 incubated at 4℃ over night.

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Product information

Protein names :ATAD2,L16,PRO2000,ATAD2_HUMAN,ATPase family AAA domain-containing protein 2

UniProtID :Q6PL18

MASS(da) :158,554

MW(kDa) :200 kDa

Form :Liquid

Purification :Protein A purification

Host :Rabbit

Isotype :IgG

sensitivity :Endogenous

Reactivity :Human

  • ApplicationDilution
  • 免疫印迹(WB)1:1000-2000
  • 免疫荧光(ICC/IF) 1:100
  • The optimal dilutions should be determined by the end user

Specificity :Antibody is produced by immunizing animals with a synthetic peptide at the sequence of human ATAD2

Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected :HeLa cells

Function : May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells..

Tissue specificity :Highly expressed in estrogen receptor positive breast tumors and in osteosarcoma tumors..

Subcellular locationi :Nucleus.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.