CD40 Rabbit mAb [2TF7]Cat NO.: A70831

Protein names ：CD40,TNFRSF5,TNR5_HUMAN,Tumor necrosis factor receptor superfamily member 5

UniProtID ：P25942

MASS(da) ：30,619

MW(kDa) ：42 kDa

Form ：Liquid

Purification ：Protein A purification

Host ：Rabbit

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Human

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• 免疫组化(IHC)1:100
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide at the sequence of human CD40

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：human tonsil

Function ： Receptor for TNFSF5/CD40LG (PubMed:31331973). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity)..

Tissue specificity ：B-cells and in primary carcinomas.

Subcellular locationi ：[Isoform I]: Cell membrane,Single-pass type I membrane protein.,[Isoform II]: Secreted.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.