COMT Rabbit mAb [AT22]Cat NO.: A77640

Protein names ：COMT,COMT_HUMAN,Catechol O-methyltransferase

UniProtID ：P21964

MASS(da) ：30,037

MW(kDa) ：24-28 kDa

Form ：Liquid

Purification ：Protein A purification

Host ：Rabbit

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Human,Mouse,Rat

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide at the sequence of human COMT

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：HEK-293T cells

Function ： Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol..

Tissue specificity ：Brain, liver, placenta, lymphocytes and erythrocytes.

Subcellular locationi ：[Isoform Soluble]: Cytoplasm.,[Isoform Membrane-bound]: Cell membrane,Single-pass type II membrane protein,Extracellular side.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.