SLC1A5/ASCT2 Rabbit mAb [9ONT]Cat NO.: A86424

Protein names ：SLC1A5,ASCT2,M7V1,RDR,RDRC,AAAT_HUMAN,Neutral amino acid transporter B )

UniProtID ：Q15758

MASS(da) ：56,598

MW(kDa) ：56 kDa

Form ：Liquid

Purification ：Protein A purification

Host ：Rabbit

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Human

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• 免疫组化(IHC)1:100
• 免疫荧光(ICC/IF) 1:100
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide at the sequence of human SLC1A5/ASCT2

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：HeLa cells

Function ： Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids (PubMed:8702519, PubMed:29872227). Through binding of the fusogenic protein syncytin-1/ERVW-1 may mediate trophoblasts syncytialization, the spontaneous fusion of their plasma membranes, an essential process in placental development (PubMed:10708449, PubMed:23492904).., (Microbial infection) Acts as a cell surface receptor for Feline endogenous virus RD114.., (Microbial infection) Acts as a cell surface receptor for Baboon M7 endogenous virus.., (Microbial infection) Acts as a cell surface receptor for type D simian retroviruses..

Tissue specificity ：Placenta, lung, skeletal muscle, kidney, pancreas, and intestine.

Subcellular locationi ：Cell membrane,Multi-pass membrane protein. Melanosome.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.