IKZF3 Rabbit mAb [110A]Cat NO.: A51842

Protein names ：IKZF3,ZNFN1A3,IKZF3_HUMAN,Zinc finger protein Aiolos

UniProtID ：Q9UKT9

MASS(da) ：58,023

MW(kDa) ：70 kDa

Form ：Liquid

Purification ：Protein A purification

Host ：Rabbit

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Human,Mouse,Rat

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• 免疫组化(IHC)1:100
• 免疫荧光(ICC/IF) 1:100
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide at the sequence of human IKZF3

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：Jurkat cells

Function ： Transcription factor that plays an important role in the regulation of lymphocyte differentiation. Plays an essential role in regulation of B-cell differentiation, proliferation and maturation to an effector state. Involved in regulating BCL2 expression and controlling apoptosis in T-cells in an IL2-dependent manner..

Tissue specificity ：Expressed most strongly in peripheral blood leukocytes, the spleen, and the thymus..

Subcellular locationi ：Nucleus. Cytoplasm.,[Isoform 1]: Nucleus.,[Isoform 3]: Nucleus.,[Isoform 11]: Nucleus.,[Isoform 14]: Nucleus. Cytoplasm.,[Isoform 12]: Cytoplasm.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.