Macrophage Inflammatory Protein 1 alpha / CCL3 + CCL3L1 Rabbit mAb [70Z8]Cat NO.: A15337

Protein names ：CCL3,G0S19-1,MIP1A,SCYA3,CCL3_HUMAN,C-C motif chemokine 3 [Cleaved into: MIP-1-alpha )]

UniProtID ：P10147

MASS(da) ：10,085

MW(kDa) ：12 kDa

Form ：Liquid

Purification ：Protein A purification

Host ：Rabbit

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Human,Mouse

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• 免疫组化(IHC)1:100
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide at the sequence of human Macrophage Inflammatory Protein 1 alpha / CCL3 + CCL3L1

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：THP-1 cells (treated with 100nM PMA for 16 hours. And then replace PMA with 100 ng/ml LPs for 4 hours and then 1 µg/ml BFA was added for the last 3 hours)

Function ： Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV)..

Subcellular locationi ：Secreted.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.