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ITPA Rabbit mAb [Q055]Cat NO.: A76550

Western blot(SDS PAGE) analysis of extracts from HEK-293T cells.Using ITPARabbit mAb [Q055] at dilution of 1:1000 incubated at 4℃ over night.

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Product information

Protein names :ITPA,C20orf37,My049,OK/SW-cl.9,ITPA_HUMAN,Inosine triphosphate pyrophosphatase

UniProtID :Q9BY32

MASS(da) :21,446

MW(kDa) :21 kDa

Form :Liquid

Purification :Protein A purification

Host :Rabbit

Isotype :IgG

sensitivity :Endogenous

Reactivity :Human

  • ApplicationDilution
  • 免疫印迹(WB)1:1000-2000
  • The optimal dilutions should be determined by the end user

Specificity :Antibody is produced by immunizing animals with a synthetic peptide at the sequence of human ITPA

Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected :HEK-293T cells

Function : Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions..

Tissue specificity :Ubiquitous. Highly expressed in heart, liver, sex glands, thyroid and adrenal gland.

Subcellular locationi :Cytoplasm.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.