Metabotropic Glutamate Receptor 2/MGLUR2 Rabbit mAb [IX1O]Cat NO.: A91100

Protein names ：GRM2,GPRC1B,MGLUR2,GRM2_HUMAN,Metabotropic glutamate receptor 2

UniProtID ：Q14416

MASS(da) ：95,568

MW(kDa) ：250 kDa

Form ：Liquid

Purification ：Protein A purification

Host ：Rabbit

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Human,Mouse,Rat

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• 免疫组化(IHC)1:100
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide at the sequence of human Metabotropic Glutamate Receptor 2/MGLUR2

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：Mouse brain

Function ： G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization..

Tissue specificity ：Detected in brain cortex (at protein level). Widely expressed in different regions of the adult brain as well as in fetal brain..

Subcellular locationi ：Cell membrane,Multi-pass membrane protein. Cell junction, synapse. Cell projection, dendrite.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.