KIF5A + KIF5B + KIF5C Rabbit mAb [FEKQ]Cat NO.: A29386

Protein names ：KIF5C,KIAA0531,NKHC2,KIF5C_HUMAN,Kinesin heavy chain isoform 5C

UniProtID ：O60282,P33176,Q12840

MASS(da) ：109,495

MW(kDa) ：117,107 kDa

Form ：Liquid

Purification ：Protein A purification

Host ：Rabbit

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Human,Mouse,Rat

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide at the sequence of human KIF5A + KIF5B + KIF5C

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：Neuro-2a cells

Function ： Involved in synaptic transmission (PubMed:24812067). Mediates dendritic trafficking of mRNAs (By similarity). Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation (By similarity)..

Tissue specificity ：Highest expression in brain, prostate and testis, and moderate expression in kidney, small intestine and ovary.

Subcellular locationi ：Cytoplasm, cytoskeleton. Cell projection, dendrite.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.