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Annexin-2/ANXA2 Rabbit mAb [VW39]Cat NO.: A26636

Western blot(SDS PAGE) analysis of extracts from HeLa cells.Using Annexin-2/ANXA2Rabbit mAb [VW39] at dilution of 1:1000 incubated at 4℃ over night.

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Product information

Protein names :ANXA2,ANX2,ANX2L4,CAL1H,LPC2D,ANXA2_HUMAN,Annexin A2

UniProtID :P07355

MASS(da) :38,604

MW(kDa) :38 kDa

Form :Liquid

Purification :Protein A purification

Host :Rabbit

Isotype :IgG

sensitivity :Endogenous

Reactivity :Human

  • ApplicationDilution
  • 免疫印迹(WB)1:1000-2000
  • 免疫组化(IHC)1:100
  • 免疫荧光(ICC/IF) 1:100
  • The optimal dilutions should be determined by the end user

Specificity :Antibody is produced by immunizing animals with a synthetic peptide at the sequence of human Annexin-2/ANXA2

Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected :HeLa cells

Function : Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9 (PubMed:18799458, PubMed:24808179, PubMed:22848640)..

Subcellular locationi :Secreted, extracellular space, extracellular matrix, basement membrane. Melanosome.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.