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Western blot(SDS PAGE) analysis of extracts from HeLa cells.Using Annexin-2/ANXA2Rabbit mAb [VW39] at dilution of 1:1000 incubated at 4℃ over night.
Protein names :ANXA2,ANX2,ANX2L4,CAL1H,LPC2D,ANXA2_HUMAN,Annexin A2
UniProtID :P07355
MASS(da) :38,604
MW(kDa) :38 kDa
Form :Liquid
Purification :Protein A purification
Host :Rabbit
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human
Specificity :Antibody is produced by immunizing animals with a synthetic peptide at the sequence of human Annexin-2/ANXA2
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :HeLa cells
Function : Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9 (PubMed:18799458, PubMed:24808179, PubMed:22848640)..
Subcellular locationi :Secreted, extracellular space, extracellular matrix, basement membrane. Melanosome.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.