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Western blot(SDS PAGE) analysis of extracts from tonsil.Using CD97Rabbit mAb [4877] at dilution of 1:1000 incubated at 4℃ over night.
Protein names :ADGRE5,CD97,AGRE5_HUMAN,Adhesion G protein-coupled receptor E5 [Cleaved into: Adhesion G protein-coupled receptor E5 subunit alpha,Adhesion G protein-coupled receptor E5 subunit beta]
UniProtID :P48960
MASS(da) :91,869
MW(kDa) :80 kDa
Form :Liquid
Purification :Protein A purification
Host :Rabbit
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human
Specificity :Antibody is produced by immunizing animals with a synthetic peptide at the sequence of human CD97
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :tonsil
Function : Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration..
Tissue specificity :Broadly expressed, found on most hematopoietic cells, including activated lymphocytes, monocytes, macrophages, dendritic cells, and granulocytes. Expressed also abundantly by smooth muscle cells. Expressed in thyroid, colorectal, gastric, esophageal and pancreatic carcinomas too. Expression are increased under inflammatory conditions in the CNS of multiple sclerosis and in synovial tissue of patients with rheumatoid arthritis. Increased expression of CD97 in the synovium is accompanied by detectable levels of soluble CD97 in the synovial fluid.
Subcellular locationi :Cell membrane,Multi-pass membrane protein.,[Adhesion G protein-coupled receptor E5 subunit alpha]: Secreted, extracellular space.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.