Caspr2/CNTNAP2 Rabbit mAb [103F]Cat NO.: A95519

Protein names ：CNTNAP2,CASPR2,KIAA0868,CNTP2_HUMAN,Contactin-associated protein-like 2

UniProtID ：Q9UHC6

MASS(da) ：148,167

MW(kDa) ：152 kDa

Form ：Liquid

Purification ：Protein A purification

Host ：Rabbit

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Human,Mouse,Rat

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• 免疫组化(IHC)1:100
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide at the sequence of human Caspr2/CNTNAP2

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：human fetal brain

Function ： Required for gap junction formation (Probable). Required, with CNTNAP1, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the juxtaparanodal region of the axo-glial junction..

Tissue specificity ：Predominantly expressed in nervous system..

Subcellular locationi ：Membrane,Single-pass type I membrane protein. Cell projection, axon. Cell junction, paranodal septate junction.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.