Angiotensin II Type 1 Receptor Rabbit mAb [BU1G]Cat NO.: A54547

Protein names ：AGTR1,AGTR1A,AGTR1B,AT2R1,AT2R1B,AGTR1_HUMAN,Type-1 angiotensin II receptor

UniProtID ：P30556

MASS(da) ：41,061

MW(kDa) ：62 kDa

Form ：Liquid

Purification ：Protein A purification

Host ：Rabbit

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Human,Mouse,Rat

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide at the sequence of human Angiotensin II Type 1 Receptor

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：C2C12 cells

Function ： Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system., (Microbial infection) During SARS coronavirus-2/SARS-CoV-2 infection, it is able to recognize and internalize the complex formed by secreted ACE2 and SARS-CoV-2 spike protein through DNM2/dynamin 2-dependent endocytosis..

Tissue specificity ：Liver, lung, adrenal and adrenocortical adenomas.

Subcellular locationi ：Cell membrane,Multi-pass membrane protein.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.