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Western blot(SDS PAGE) analysis of extracts from U266B1 cells .Using BCMARabbit mAb [8BE3] at dilution of 1:1000 incubated at 4℃ over night.
Protein names :TNFRSF17,BCM,BCMA,TNR17_HUMAN,Tumor necrosis factor receptor superfamily member 17
UniProtID :Q02223
MASS(da) :20,165
MW(kDa) :19 kDa
Form :Liquid
Purification :Protein A purification
Host :Rabbit
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human
Specificity :Antibody is produced by immunizing animals with a synthetic peptide at the sequence of human BCMA
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :U266B1 cells
Function : Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK..
Tissue specificity :Expressed in mature B-cells, but not in T-cells or monocytes.
Subcellular locationi :Cell membrane,Single-pass type III membrane protein. Endomembrane system,Single-pass type III membrane protein.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.