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Western blot(SDS PAGE) analysis of extracts from 293T cells lysates.Using PBR Rabbit mAb IgG [BN1I] at dilution of 1:1000 incubated at 4℃ over night.
Protein names :TSPO,BZRP,MBR,TSPO_HUMAN,Translocator protein
UniProtID :P30536
MASS(da) :18,828
MW(kDa) :19
Form :Liquid
Purification :Protein A purification
Host :Rabbit
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human,Mouse
Specificity :Antibody is produced by immunizing animals with a synthetic peptide at the sequence of human PBR.
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :293T cells lysates
Function : Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme (By similarity). Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism (PubMed:24814875), but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor,can also bind isoquinoline carboxamides (PubMed:1847678)..
Tissue specificity :Found in many tissue types. Expressed at the highest levels under normal conditions in tissues that synthesize steroids..
Subcellular locationi :Mitochondrion membrane,Multi-pass membrane protein.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.