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Western blot(SDS PAGE) analysis of extracts from human lung lysates.Using Von Willebrand Factor Rabbit mAb IgG [4888] at dilution of 1:1000 incubated at 4℃ over night.
Protein names :VWF,F8VWF,VWF_HUMAN,von Willebrand factor [Cleaved into: von Willebrand antigen 2 ]
UniProtID :P04275
MASS(da) :309,265
MW(kDa) :310460
Form :Liquid
Purification :Protein A purification
Host :Rabbit
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human
Specificity :Antibody is produced by immunizing animals with a synthetic peptide at the sequence of human Von Willebrand Factor.
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :human lung lysates
Function : Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.
Tissue specificity :Plasma.
Subcellular locationi :Secreted. Secreted, extracellular space, extracellular matrix.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.