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Western blot(SDS PAGE) analysis of extracts from mouse placenta lysates.Using RHEB Rabbit mAb IgG [TUA9] at dilution of 1:1000 incubated at 4℃ over night.
Protein names :RHEB,RHEB2,RHEB_HUMAN,GTP-binding protein Rheb
UniProtID :Q15382
MASS(da) :20,497
MW(kDa) :20
Form :Liquid
Purification :Protein A purification
Host :Rabbit
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human,Mouse
Specificity :Antibody is produced by immunizing animals with a synthetic peptide at the sequence of human RHEB.
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :mouse placenta lysates
Function : Activates the protein kinase activity of mTORC1, and thereby plays a role in the regulation of apoptosis. Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Has low intrinsic GTPase activity..
Tissue specificity :Ubiquitous. Highest levels observed in skeletal and cardiac muscle..
Subcellular locationi :Endomembrane system,Lipid-anchor,Cytoplasmic side. Golgi apparatus membrane,Lipid-anchor,Cytoplasmic side. Cytoplasm, cytosol. Endoplasmic reticulum membrane,Lipid-anchor,Cytoplasmic side.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.