Fatty Acid Synthase Rabbit mAb[6676]Cat NO.: A74444

Protein names ：FASN,FAS,FAS_HUMAN,Fatty acid synthase [Includes: [Acyl-carrier-protein] S-acetyltransferase ,[Acyl-carrier-protein] S-malonyltransferase ,3-oxoacyl-[acyl-carrier-protein] synthase ,3-oxoacyl-[acyl-carrier-protein] reductase ,3-hydroxyacyl-[acyl-carrier

UniProtID ：P49327

MASS(da) ：273,427

MW(kDa) ：273

Form ：Liquid

Purification ：Protein A purification

Host ：Rabbit

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Human,Mouse,Rat

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000,
• 免疫组化(IHC)1:100
• 免疫荧光(ICC/IF) 1:100,
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide at the sequence of human Fatty Acid Synthase.

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：MCF-7 cells lysates

Function ： Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain.., (Microbial infection) Fatty acid synthetase activity is required for SARS coronavirus-2/SARS-CoV-2 replication..

Tissue specificity ：Ubiquitous. Prominent expression in brain, lung, liver and mammary gland..

Subcellular locationi ：Cytoplasm. Melanosome.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.