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Western blot(SDS PAGE) analysis of extracts from HeLa cells.Using AHA1 Rabbit mAb IgG [95IL] at dilution of 1:1000 incubated at 4℃ over night.
Protein names :AHSA1,C14orf3,HSPC322,AHSA1_HUMAN,Activator of 90 kDa heat shock protein ATPase homolog 1
UniProtID :O95433
MASS(da) :38,274
MW(kDa) :43kDa
Form :Liquid
Purification :Protein A purification
Host :Rabbit
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human,Mouse,Rat
Specificity :Antibody is produced by immunizing animals with a synthetic peptide of human AHA1.
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :HeLa cells
Function : Acts as a co-chaperone of HSP90AA1 (PubMed:29127155). Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity (PubMed:29127155). Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:27353360). Competes with the inhibitory co-chaperone TSC1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:29127155)..
Tissue specificity :Expressed in numerous tissues, including brain, heart, skeletal muscle and kidney and, at lower levels, liver and placenta..
Subcellular locationi :Cytoplasm, cytosol. Endoplasmic reticulum.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.