Alpha-1 Antitrypsin (SERPINA1) Rabbit mAb[F7ZS]Cat NO.: A83491

Protein names ：SERPINA1,AAT,PI,PRO0684,PRO2209,A1AT_HUMAN,Alpha-1-antitrypsin [Cleaved into: Short peptide from AAT ]

UniProtID ：P01009

MASS(da) ：46,737

MW(kDa) ：45kDa

Form ：Liquid

Purification ：Protein A purification

Host ：Rabbit

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Mouse,Rat

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide of Mouse Alpha-1 Antitrypsin (SERPINA1).

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：Mouse lung tissue lysate

Function ： Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin., [Short peptide from AAT]: Reversible chymotrypsin inhibitor. It also inhibits elastase, but not trypsin. Its major physiological function is the protection of the lower respiratory tract against proteolytic destruction by human leukocyte elastase (HLE).

Tissue specificity ：Ubiquitous. Expressed in leukocytes and plasma..

Subcellular locationi ：Secreted. Endoplasmic reticulum.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.