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Western blot(SDS PAGE) analysis of extracts from Mouse lung tissue lysate.Using Caveolin-3Rabbit mAb IgG [M04Z] at dilution of 1:1000 incubated at 4℃ over night.
Protein names :CAV3,CAV3_HUMAN,Caveolin-3
UniProtID :P56539
MASS(da) :17,259
MW(kDa) :19KDa
Form :Liquid
Purification :Protein A purification
Host :Rabbit
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human,Mouse,Rat
Specificity :Antibody is produced by immunizing animals with a synthetic peptide of human Caveolin-3 .
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :Mouse lung tissue lysate
Function : May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. May also regulate voltage-gated potassium channels. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress (By similarity). Mediates the recruitment of CAVIN2 and CAVIN3 proteins to the caveolae (PubMed:19262564)..
Tissue specificity :Expressed predominantly in muscle..
Subcellular locationi :Golgi apparatus membrane,Peripheral membrane protein. Cell membrane,Peripheral membrane protein. Membrane, caveola,Peripheral membrane protein. Cell membrane, sarcolemma.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.