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Western blot(SDS PAGE) analysis of extracts from Raji cells.Using ELMO1 Rabbit mAb IgG [6581] at dilution of 1:1000 incubated at 4℃ over night.
Protein names :ELMO1,KIAA0281,ELMO1_HUMAN,Engulfment and cell motility protein 1
UniProtID :Q92556
MASS(da) :83,829
MW(kDa) :85kDa
Form :Liquid
Purification :Protein A purification
Host :Rabbit
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human,Mouse,Rat
Specificity :Antibody is produced by immunizing animals with a synthetic peptide of human ELMO1.
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :Raji cells
Function : Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1..
Tissue specificity :Widely expressed, with a higher expression in the spleen and placenta.
Subcellular locationi :Cytoplasm. Cell membrane.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.