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Western blot(SDS PAGE) analysis of extracts from HeLa cells.Using EWSR1 Rabbit mAb IgG [0L9S] at dilution of 1:1000 incubated at 4℃ over night.
Protein names :EWSR1,EWS,EWS_HUMAN,RNA-binding protein EWS
UniProtID :Q01844
MASS(da) :68,478
MW(kDa) :90kDa
Form :Liquid
Purification :Protein A purification
Host :Rabbit
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human,Mouse,Rat
Specificity :Antibody is produced by immunizing animals with a synthetic peptide of human EWSR1.
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :HeLa cells
Function : Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.
Tissue specificity :Ubiquitous.
Subcellular locationi :Nucleus. Cytoplasm. Cell membrane.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.