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Western blot(SDS PAGE) analysis of extracts from Mouse heart tissue lysate.Using FHL2 Rabbit mAb IgG [527M] at dilution of 1:1000 incubated at 4℃ over night.
Protein names :FHL2,DRAL,SLIM3,FHL2_HUMAN,Four and a half LIM domains protein 2
UniProtID :Q14192
MASS(da) :32,193
MW(kDa) :32kDa
Form :Liquid
Purification :Protein A purification
Host :Rabbit
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human,Mouse,Rat
Specificity :Antibody is produced by immunizing animals with a synthetic peptide of human FHL2.
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :Mouse heart tissue lysate
Function : May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation. Negatively regulates the calcineurin/NFAT signaling pathway in cardiomyocytes (PubMed:28717008)..
Tissue specificity :Expressed in skeletal muscle and heart..
Subcellular locationi :Cytoplasm. Nucleus. Cytoplasm, myofibril, sarcomere, Z line.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.