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Western blot(SDS PAGE) analysis of extracts from Mouse brain tissue lysate.Using FKBP12 Rabbit mAb IgG [0I9X] at dilution of 1:1000 incubated at 4℃ over night.
Protein names :FKBP1A,FKBP1,FKBP12,FKB1A_HUMAN,Peptidyl-prolyl cis-trans isomerase FKBP1A
UniProtID :P62942
MASS(da) :11,951
MW(kDa) :12kDa
Form :Liquid
Purification :Protein A purification
Host :Rabbit
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human,Mouse,Rat
Specificity :Antibody is produced by immunizing animals with a synthetic peptide of human FKBP12.
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :Mouse brain tissue lysate
Function : Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruits SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides..
Subcellular locationi :Cytoplasm, cytosol. Sarcoplasmic reticulum membrane,Peripheral membrane protein,Cytoplasmic side.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.